The effect of honeybee-collected pollen lump extract on lower urinary tract symptoms with benign prostatic enlargement - A double-blind, placebo-controlled clinical trial -

The effect of honeybee-collected pollen lump extract on lower urinary tract symptoms with benign prostatic enlargement - A double-blind, placebo-controlled clinical trial - - The effect of honeybee-collected pollen lump extract on lower urinary tract symptoms with benign prostatic enlargement

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025094

Enrollment

160

Registered

2016-12-24

Start date

2017-01-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

benign prostatic enlargement

Interventions

the feeding of honeybee-collected pollen lump extract the feeding of the placebo food

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: treatment naive out patients n with total International Prostate Symptom Score (IPSS) more than 4 and < 12.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had neurogenic bladder dysfunction, bladder calculi, or active urinary tract infection: had severe cardiac disease, renal dysfunction (serum creatinine levels more than 2 mg/dL), and hepatic dysfunction (aspartate and alanine aminotransferase concentrations more than twice the normal values).

Design outcomes

Primary

Measure	Time frame
the change of international prostatic symptoms score before and after feeding of honeybee-collected pollen lump extract	—

Countries

Japan

Contacts

Public ContactYoshihisa Matsukawa

Nagoya University Graduate School of Medicine Department of Urology

yoshi44@med.nagoya-u.ac.jp+81-52-744-2985

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026