refractory epilepsy patients
Conditions
Interventions
Sponsors
Yokohama City University, School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.refractory epilepsy patients(mesial temporal lobe epilepsy) 2.patinets for anterior temporal lobectomy(ATL) 3.patients who are without cerebral surgery on the same side of ATL 4.patients who are 20 years or older 5.patients who can consent to this study by oneself
Exclusion criteria
Exclusion criteria: 1.patients who have significant abnormalities insides the brains 2.patients who have experienced the electric stimulation therapy 3.patients who undergo artificial dialysis 4.patients who have severe liver dysfunction 5.patients who have tatoo 6.claustrophobic patients 7.breast-feeding mothers, expecting mothers, females who desire to be a mother 8.patients who desire to bear a child within this study period 9.patients who take Fycompa 10.patients who underwent nuclear medicine examination within one-week before this registarion 11.patients who underwent other clinical trials using unapproved nuclear medicine examination within six month before this registarion 12.patients who underwent other clinical trials within 12 weeks before this registarion 13.patients whom study doctors consider unappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlation of the AMPA receptors densities examined by biochemical study and [11C]K-2 PET study | — |
Secondary
| Measure | Time frame |
|---|---|
| The adverse events occured in patients during 7days after PET scan | — |
Countries
Japan
Contacts
Public Contactsano akane
Yokohama City University, School of Medicine Department of Physiology
Outcome results
None listed