The Comparison of Diagnostic Performance of Fractional Flow Reserve between the use of 4 Fr and 6 Fr catheters in Intermediate Coronary Artery Stenosis

The Comparison of Diagnostic Performance of Fractional Flow Reserve between the use of 4 Fr and 6 Fr catheters in Intermediate Coronary Artery Stenosis - COmparison of Fractional Flow Reserve Measurements through 4 FrEnch versus 6 FrEnch Diagnostic Catheter - COFFEE trial -

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025089

Enrollment

Registered

2016-11-30

Start date

2016-10-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are indicated for coronary angiography or coronary intervention. 2) Patients with more than 50% stenosis in main coronary artery 3) Patients with indicated FFR value (more than 0.70, less than 0.90), measured by 4Fr diagnostic catheter

Exclusion criteria

Exclusion criteria: 1) Patients who are contraindicated to adenosine 2) Patients who have bronchial asthma 3) Patients who have a second degree of AV block or third degree of AV block. 4) Patients who have hemodialysis 5) Patients who have severe renal dysfunction (Crea; more than 2.0mg/dL) 6) Inadequate lesion for FFR measurement 7) Patients with unstable hemodynamic conditions 8) Patients with LVEF less than 30%

Design outcomes

Primary

Measure	Time frame
Correlation of FFR value measured by 4Fr and 6Fr catheters	—

Countries

Japan

Contacts

Public ContactNoriaki Moriyama

Shonankamakura General Hospital Department of Cardiology and Catheterization Laboratory

e2718nm@gmail.com0467-46-1717

Outcome results