Biotin supplement for very low birth weight infant

Biotin supplement for very low birth weight infant - Biotin for very low birth weight infant

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025088

Enrollment

150

Registered

2017-01-01

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

very low birth weight infant

Interventions

oral supplementation of biotin 0.5mg once a day from the third day of life to the day of discharge

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: very low birth weight infants born at our hospital

Exclusion criteria

Exclusion criteria: congenital malformation syndrome abnormalities of chromosome

Design outcomes

Primary

Measure	Time frame
late onset metabolic acidosis for 3-8 weeks of age	—

Secondary

Measure	Time frame
mortality at discharge neurological morbidity at the age of two years	—

Countries

Japan

Contacts

Public ContactKenichi Suga

Tokushima University Hospital Pediatrics

suga.kenichi.1@tokushima-u.ac.jp+81-88-633-9555

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026