Arthritis
Conditions
Interventions
None listed
Sponsors
Gunma University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who underwent FDG-PET for the following purpose: 1. Clinical trial: FDG-PET for rheumatoid arthritis 2. Patient with non rheumatoid arthritis who underwent FDG-PET for suspicion of malignancy
Exclusion criteria
Exclusion criteria: Patients without arthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study involved patients, who had rheumatoid arthritis or seronegative arthopathy (Non-RA). The FDG PET images were taken 1 hour after injection of 18F-FDG and scanned from head to toe in arms down position using a PET-CT scanner. FDG uptake was analyzed visually in each joint using Visual Scoring System (VS) from Score 1 to Score 5 and quantified as maximum SUV (SUVmax) in a standard region of interest. A total of 12 joints were evaluated in each patient. Metabolic parameters, metabolic active volume (MAV) and total lesion glycolysis (MAV X SUVmean) was also calculated. Each sum of Visual score (total visual score), SUVmax (total SUVmax), MAV (total MAV), and total lesion glycolysis (total TLG) was calculated for each patient. Thresholds to measure MAVs and TLGs were decided by ROC analysis based on the comparison with VS and SUVmax. All the parameters were compared between RA and Non-RA group. | — |
Countries
Japan
Contacts
Public ContactNakajima Takahito
Gunma University Hospital Diagnostic Radiology and Nuclear Medicine
Outcome results
None listed