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The association between ABO blood group and polypharmacy: does blood group O have an affinity for medications? A retrospective and prospective cross-sectional study.

The association between ABO blood group and polypharmacy: does blood group O have an affinity for medications? A retrospective and prospective cross-sectional study. - The association between ABO blood group and polypharmacy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000025066
Enrollment
340
Registered
2016-11-30
Start date
2017-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polypharmacy in elderly patients

Interventions

None listed

Sponsors

National Hospital Organization Tochigi Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria for primary objective 1) Hip fracture patients aged 65 years or older Inclusion criteria for secondary objective 1) Patients aged 65 years or older hospitalized for orthopaedic reasons 2) Five or more prescribed medications at admission 3) Pharmacists explained and recommended the interventions to improve polypharmacy

Exclusion criteria

Exclusion criteria: Exclusion criteria for primary objective 1) A second admission due to a hip fracture during the study period 2) Hip fracture was not confirmed by X-ray after admission 3) ABO blood typing was not performed Exclusion criteria for secondary objective 1) A second or third contact by pharmacists during another admission 2) ABO blood typing was not performed

Design outcomes

Primary

MeasureTime frame
the difference between blood group O and non-O blood groups in the proportion of polypharmacy at admission

Secondary

MeasureTime frame
the difference between blood group O and non-O blood groups in the rate of refusal to undergo deprescription during the hospital stay

Countries

Japan

Contacts

Public ContactJunpei Komagamine

National Hospital Organization Tochigi Medical Center Internal medicine

jkomagamine@tochigi-mc.jp028-622-5241

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026