Examination of the effect of dexmedetomidine on reperfusion injury due to isolated pulmonary ventilation

Examination of the effect of dexmedetomidine on reperfusion injury due to isolated pulmonary ventilation - Examination of the effect of dexmedetomidine on reperfusion injury due to isolated pulmonary ventilation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025051

Enrollment

Registered

2016-11-29

Start date

2015-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reperfusion injury

Interventions

Dexmedetomidine administered group Control/Saline group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo lung resection with isolated lung ventilation and enter ICU after surgery

Exclusion criteria

Exclusion criteria: Allergic to Dexmedetomidine lung and systemic inflammatory diseases BMI 35 over reoperative patients patients with impaired cardiac function Hugh Jones classification 4 or more autoimmune disease immunosuppressive agent administration Patients who are not indicated for extramembrane anesthesia

Design outcomes

Primary

Measure	Time frame
Inflammatory cytokines in serum	—

Secondary

Measure	Time frame
Vital, blood gas analysis, postoperative pain, resected lung weight, general blood sampling before and after surgery, extent of postoperative sedation, amount of urine, postoperative complications, days of stay in ICU, days to stay in hospital etc	—

Countries

Japan

Contacts

Public ContactAmane Konishi

Ehime University Graduate School of Medicine Department of Anesthesia and Perioperative Medicine

konishi.amane.cs@ehime-u.ac.jp089-960-5383

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026