Usefulness of cardiac computed tomography in aortic stenosis patients

Usefulness of cardiac computed tomography in aortic stenosis patients - Usefulness of cardiac computed tomography in aortic stenosis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025047

Enrollment

200

Registered

2016-12-01

Start date

2016-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients who were diagnosed with aortic stenosis clinically and underwent coronary CT angiography 2.Over 20 years old

Exclusion criteria

Exclusion criteria: 1.Clinically unstable patients (Acute myocardial infarction, unstable angina, and malignant arrhythmia) 2.Patients with a history of hypersensitivity to iodine or iodinated contrast media 3.Patients who are pregnant or breastfeeding 4.When the research director or the research subinvestigator determines that it is not appropriate to participate in the research

Design outcomes

Primary

Measure	Time frame
To evaluate the feasibility of left ventricular CT MP-strain, LIE-CT, CT-ECV for predicting outcome: all-cause mortality, cardiac death, hospitalization due to heart failure, therapeutic effect (aortic valve replacement, transcatheter aortic valve implantation, transcatheter aortic valve replacement )	—

Secondary

Measure	Time frame
1) To evaluate CT MP-strain value compared with strain value derived from cardiac MRI or US. 2) To compare CT MP-strain with cardiac anatomical, functional or myocardial characteristic information measured by cardiac MRI or US (left ventricular ejection fraction, wall thickness, myocardial volume, late gadolinium enhancement, T1 mapping, T2 mapping, phase contrast) 3) To evaluate other parameters from CT strain analysis (Strain rate, minimum principal strain etc.) 4) To evaluate LIE-CT/CT-ECV derived from cardiac CT compared with LGE-MRI/ECV derived from cardiac MRI.	—

Measure

Time frame

1) To evaluate CT MP-strain value compared with strain value derived from cardiac MRI or US. 2) To compare CT MP-strain with cardiac anatomical, functional or myocardial characteristic information measured by cardiac MRI or US (left ventricular ejection fraction, wall thickness, myocardial volume, late gadolinium enhancement, T1 mapping, T2 mapping, phase contrast) 3) To evaluate other parameters from CT strain analysis (Strain rate, minimum principal strain etc.) 4) To evaluate LIE-CT/CT-ECV derived from cardiac CT compared with LGE-MRI/ECV derived from cardiac MRI.

—

Countries

Japan

Contacts

Public ContactYuki Tanabe

Ehime University Graduate School of Medicine Department of Radiology

yuki.tanabe.0225@gmail.com089-960-5371

Outcome results