Mood disorder
Conditions
Interventions
TDCS treatment is performed from once a week to once a month for one year. I plan to stimulate 1-2 mA for 20-30 minutes.
Sponsors
Department of Neuropsychiatry,Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1,Patient in a mood disorder with intractable depressive symptoms during visit to the psychiatry department affiliated hospital of the University of the Ryukyus 2,Age 16 years older, under 65 years old 3,In the past,used more than two kinds of antidepressants (treatment amount on the package insert) and a sufficient period (4 weeks or more) but in Montgomery - Asberg Depression Scale (MADRS) more than 20 4,Persons whose disease duration is one year or more 5,Regarding participation in this research, a person who gained written consent by the patient's free will and consent was obtained by the substitute.
Exclusion criteria
Exclusion criteria: 1,person with a history of head trauma accompanied by consciousness disturbance of 5 minutes or more 2,Persons who have a history of organic diseases in the brain 3,Person who has history of substance dependence or present symptom 4,Persons who have a history of confusion conscious convulsions 5,Persons who have a history of chronic headache 6,Pregnant or potential women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the remission rate of depression 1 month, 3 months, 6 months, 1 year after treatment start. | — |
Secondary
| Measure | Time frame |
|---|---|
| Remission maintenance rate one year after the start of treatment, each item of neuropsychological examination and various biological indicators, changes in various brain function images | — |
Countries
Japan
Contacts
Public ContactHotaka Shinzato
Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan Department of Neuropsychiatry
Outcome results
None listed