A research of the effect of mineral water consumption derived from Nagayu hot spring on prediabetes patients

A research of the effect of mineral water consumption derived from Nagayu hot spring on prediabetes patients - A research of the effect of mineral water consumption on prediabetes patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024916

Enrollment

Registered

2016-11-20

Start date

2016-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prediabetes

Interventions

(1) Consumption of tap water for 28 days. Consumption of 500 ml of tap water divided into thrice daily (30-60 minutes before breakfast, lunch, and dinner). (2) Consumption of mineral water that colle

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Males and females aged 20 or above. 2) Subjects who live around Nagayu hot spring area. 3) Subjects whose HbA1c (NGSP) values are ranged from 5.6 to 6.4%. 4) Subjects who show understanding of the study procedures and agreement with participating the study by written informed consent prior to the study.

Exclusion criteria

Exclusion criteria: 1) Subjects who frequently consume mineral water that collected from Nagayu hot spring. 2) Subjects who consume medicine daily.

Design outcomes

Primary

Measure	Time frame
Clinical blood test (HbA1c, glycoalbumin, blood glucose, insulin) 16S metagenome analysis of gut microbiota Metabolome analysis of intestinal metabolites	—

Secondary

Measure	Time frame
Gastrointestinal Symptom Rating Scale (GSRS), Japanese edition Questionnaire Body weight Body Mass Index (BMI)	—

Countries

Japan

Contacts

Public ContactShinnosuke Murakami

Metagen, Inc. Headquarters

murakami@metagen.co.jp+81-235-64-0330

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026