Oral Diseases
Conditions
Interventions
Cessation intervention with or without NRT(nicitine replace therapy using nicitine patch or nicotine gum) for 12 weeks for those who intention to abstinence from smoking and having 3 points or more in
Sponsors
Tobacco Cessation Intervention Study Team for Oral Diseases (TISOD)
Japanese Association for Dental Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Periodontitis patients who have 30% or more of the sites with 4 mm or more probing pocket depth and 3 sites or more with 6 mm or more probing depth Patients for implant treatment; about to implant placement for their tooth loss Oral mucosal diseases; having a pathological diagnosis and clinically diagnosed for nicotine stomatitis, oral leukoplakia, erythloplakia and oral lichen planus
Exclusion criteria
Exclusion criteria: Less than 20 years old Already having any cessation intervention Having had periodontal treatment within 6 months Periodontitis patients who have anti-inflammatory drug or steroid use Patients for implant treatment; N/A Oral mucosal diseases; have had surgical resections before or other interventional treatments In case of use of nicotine replacement therapy (NRT);already have a prescription of NRTs or medicines, pregnant and breastfeeding women, has unstable angina pectoris, in the immediate (within 3 months) past myocardial infarction period, have serious arrhythmias, post-percutaneous coronary intervention (PCI), post-coronary artery bypass graft (CABG), early period of recovery from cerebrovascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical improvement of each disease (12 months after the treatment) Periodontitis- Probing pocket depth and clinical attachment level of two sites with the deepest periodontal pocket (6 mm or more) Implant- one-year implant survival and per-implant marginal bone loss the day after implant placement and after 1 year measured by a standardized X-ray photo Oral mucosal diseases-size reduction (major x minor axis /mm) at a predominant site for non-surgical group and recurrence rate for surgical group | — |
Secondary
| Measure | Time frame |
|---|---|
| Tobacco abstinence rate at each observation period at 3, 6, 12, 24 months for each disease group | — |
Countries
Japan
Contacts
Public ContactHitoshi Nagasu
Japanese Academy of Maxillofacial Implant Secretariat
Outcome results
None listed