A study for decreasing effects of yogurt containing Lactobacillus gasseri PA-3 on the serum uric acid levels

A study for decreasing effects of yogurt containing Lactobacillus gasseri PA-3 on the serum uric acid levels - A study for decreasing effects of yogurt on the serum uric acid levels

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024866

Enrollment

240

Registered

2016-11-16

Start date

2016-11-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Consumption of yogurt containing Lactobacillus gasseri PA-3 for 8 weeks Consumption of yogurt without Lactobacillus gasseri PA-3 for 8 weeks

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Male subjects aged twenty or more 2) Subjects who have a serum uric acid level of 5.0 mg / dL or more and 7.0 mg / dL or less for screening 1st and 2nd 3) Subjects who can understand the purpose and the contents of this study, and can agree to participation to this study by letter

Exclusion criteria

Exclusion criteria: 1) Subjects who are instructed pharmacotherapy for hyperuricemia or gout or life guidance by physician 2) Subjects who have the past medical history of gout 3) Subjects who routinely take Meiji Probio Yogurt PA-3 4) Subjects who routinely take health food effective for reducing serum uric acid levels 5) Subjects who routinely intensive exercises 6) Among subjects who have or have a history of urinary tract infections, liver diseases, heart diseases, urolithiasis, renal disorders, hypertension, diabetes mellitus, subjects who are undergoing pharmacotherapy or who are planning to receive pharmacotherapy during the study 7) Subjects who are routinely unbalanced on dietary habits 8) Subjects who show allergic responses to dairy products 9) Subjects who have participated in other clinical tests within the past one month 10) Subjects who were judged inadequate by investigator for other reasons

Design outcomes

Primary

Measure	Time frame
Serum uric acid level and change	—

Secondary

Measure	Time frame
1) AST(GOT), ALT(GPT),gamma-GTP, ALP, LDH, total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride , urea nitrogen, serum creatinine, blood sugar, HbA1c, Na, Cl, K and change 2) urine creatinine, urine uric acid and change 3) body weight, BMI and change 4) blood pressure, pulse rate and change 5) the amount of urinary excretion of uric acid, uric acid clearance, creatinine clearance, the rate of urinary excretion of uric acid and change	—

Measure

Time frame

1) AST(GOT), ALT(GPT),gamma-GTP, ALP, LDH, total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride , urea nitrogen, serum creatinine, blood sugar, HbA1c, Na, Cl, K and change 2) urine creatinine, urine uric acid and change 3) body weight, BMI and change 4) blood pressure, pulse rate and change 5) the amount of urinary excretion of uric acid, uric acid clearance, creatinine clearance, the rate of urinary excretion of uric acid and change

—

Countries

Japan

Contacts

Public ContactMasanori Ito

Mebix, Inc. Research Promotion Group

yogurt-pa3@mebix.co.jp03-4362-4507

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026