Perioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomy

Perioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomy - Perioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024849

Enrollment

Registered

2016-11-16

Start date

2016-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

administration of placebo 4 days before to 13 days after surgery administration of Cystine and Theanine 4 days before to 13 days after surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Indication for thoracoscopic esophagectomy in a prone position (gastric conduit is selected for reconstruction) (2) clinical Stage I - III (without T4 disease) (3) Patients must be at a score level 0 - 1 of ECOG performance status (4) Written informed consent must be obtained from patients

Exclusion criteria

Exclusion criteria: (1) Active infection (2) Poorly controlled hypertension (3) Poorly controlled diabetes mellitus (4) Patients with severe underlying circulatory disease (5) Participate in other study (6) Inability to take food orally (7) Need for intravenous amino acid infusion

Design outcomes

Primary

Measure	Time frame
physical activity measured by an activity monitor	—

Countries

Japan

Contacts

Public ContactTadashi Sakurai

Tohoku University Division of Advanced Surgical and Science and Technology

tsakurai@med.tohoku.ac.jp022-717-7214

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026