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A research for clinical application of real-time functional magnetic resonance imaging neurofeedback for treatment of schizophrenia

A research for clinical application of real-time functional magnetic resonance imaging neurofeedback for treatment of schizophrenia - A research for clinical application of real-time functional magnetic resonance imaging neurofeedback for treatment of schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024831
Enrollment
25
Registered
2017-02-01
Start date
2017-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

One NFB session in fMRI scanner will be conducted once a day, and 5 days a week. After 5-10 sessions (in one or 2 weeks), symptoms and conditions of participants will be evaluated. N-back cognitive

Sponsors

Kyoto University
Lead Sponsor
Advanced Telecommunications Research Institute International (ATR)
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants need to be outpatients of department of psychiatry, Kyoto University. 2. Participants need to be diagnosed as schizophrenia and other psychotic disorders, or schizophrenia spectrum in DSM-IV-TR or DSM-V. 3. Participants need to have normal or corrected visual acuity. 4. Age at the time of enrolment need to be over 20 years old and under 50 years old. 5. Participants need to give informed consent by themselves on paper.

Exclusion criteria

Exclusion criteria: 1. User of cardiac pacemaker 2. User of brain vascular clip 3. User of electric stimulator for neurons 4. User of implanted pump in body 5. One having remaining metallic piece in one's body 6. One having tattoo 7. One having treatment with electroconvulsive therapy 8. One having comorbid disorder below, Seizure or other neurological disease Substance related disorders Severe heart disease 9. One having past history below, Seizure or other neurological disease Substance related disorders Brain injury with loss of consciousness 10. Female having possibility of pregnancy. Female having breast-feeding. Male of Female not using birth control during research 11. One having been judged as inappropriate for research by researcher and doctors.

Design outcomes

Primary

MeasureTime frame
Positive and Negative Symptoms Scale (PANSS)

Secondary

MeasureTime frame
The Global Assessment of Functioning (GAF) The Brief Assessment of Cognition in Schizophrenia (BACS)

Countries

Japan

Contacts

Public ContactYujiro Yoshihara

Kyoto University Graduate School of Medicine Department of Psychiatry

yujiroyo@kuhp.kyoto-u.ac.jp0757514947

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026