Effect of cognitive behavioral therapy and brain alteration in post-traumatic stress disorder

Effect of cognitive behavioral therapy and brain alteration in post-traumatic stress disorder - Effect of CBT and MRI change in PTSD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024791

Enrollment

Registered

2016-11-10

Start date

2015-10-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-traumatic stress disorder

Interventions

cognitive behavioral therapy (prolonged exposure: PE, 10-15 weekly 120-minite session).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: To meet the diagnostic criteria for PTSD induced by sexual violence who remains moderate or severe symptoms (IES-R>=25).

Exclusion criteria

Exclusion criteria: Individuals who have history of organic disease in the brain, schizophrenia, or other psychiatric disorder. Individuals who have histories of alcoholic or substance abuse within 12 months. Individuals who have active suicidality.

Design outcomes

Primary

Measure	Time frame
CAPS, IES-R, PTCI, SF-36	—

Secondary

Measure	Time frame
CES-D, structural and functional MRI	—

Countries

Japan

Contacts

Public ContactYoshiyuki Hirano

Chiba University Research Center for Child Mental Development

hirano@chiba-u.jp0432262975

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026