Clinical benefit for diabetic vascular complication on non-invasive measurement of advanced glycogen endproduct level in type 2 diabetes

Clinical benefit for diabetic vascular complication on non-invasive measurement of advanced glycogen endproduct level in type 2 diabetes - Clinical benefit for diabetic vascular complication on non-invasive measurement of advanced glycogen endproduct level in type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000024756

Enrollment

600

Registered

2016-11-08

Start date

2017-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We will recruit 600 patients with type 2 diabetes who were hospitalized for glycemic control in Kumamoto University Hospital, Kagoshima University Hospital or Fukuoka University Hospital.

Exclusion criteria

Exclusion criteria: 1. Patients with infectious disease 2. Patients with acute/chronic inflammatory disease 3. Patients with cancer 4. Patients with acute cerebrovascular disease 5. Patients with severe hepatic disease 6. Patients with severe respiratory 7. Patients with mental disorder 8. Patients decided from attended doctors not to be recruited in the study

Design outcomes

Primary

Measure	Time frame
Correlation between amounts of AGE constructs and degree of autofluorescence by irradiation of light and other experimental markers for macro- and micro-angiopathy (leukocyte counts, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, total protein, serum albumin, serum creatinin, BUN, UA, AST, ALT, LDH, CHE, ALP, g-GTP, total bilirubin, creatin kinase, fasting glucose level, fasting serum insulin level, HbA1c, glycated albumin, hs-CRP, urinaly albumin level, urinaly creatinin, mean- and max-IMT, baPWV, degree of retinopathy, degree of neuropathy, and degree of nephropathy.	—

Measure

Time frame

Correlation between amounts of AGE constructs and degree of autofluorescence by irradiation of light and other experimental markers for macro- and micro-angiopathy (leukocyte counts, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, total protein, serum albumin, serum creatinin, BUN, UA, AST, ALT, LDH, CHE, ALP, g-GTP, total bilirubin, creatin kinase, fasting glucose level, fasting serum insulin level, HbA1c, glycated albumin, hs-CRP, urinaly albumin level, urinaly creatinin, mean- and max-IMT, baPWV, degree of retinopathy, degree of neuropathy, and degree of nephropathy.

—

Countries

Japan

Contacts

Public ContactTAKESHI MATSUMURA

Kumamoto University Hospital Diabetes, Metabolism and Endocrinology

takeshim@gpo.kumamoto-u.ac.jp0963439113

Outcome results