Prospective study of FFR CT use for the triage of ACS in the emergency department

Prospective study of FFR CT use for the triage of ACS in the emergency department - FFR CT ACS study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024746

Enrollment

250

Registered

2019-09-01

Start date

2016-09-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chest pain patients with ACS

Interventions

Acute chest pain patients with high probability ACS will undergo FFR CT and then coronary angio with FFR

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Acute chest pain with ECG in favor of ACS, troponin T hs >0,052 or rise 0-1 hour > 0,005 ng/l using Elecsys method, GRACE score >109, no ESC criteria for urgent angio

Exclusion criteria

Exclusion criteria: no informed consent, limited life expectancy<2 years, pregnancy, other cardiac or non-cardiac diagnosis for acute chest pain, high risk ACS, previous CABG or PCI, recent ACS <6 months, arrhythmia, shock, acute heart failure, complications due to ACS, dynamic STT changes with ST elevation, contrast allergy, renal insufficiency, contra-indication to beta blockers, nitrates or adenosine, CHD

Design outcomes

Primary

Measure	Time frame
accuracy analysis of FFR CT (sensitivity, specificity, positive and negative predictive values and ROC analysis comparison with invasive FFR	—

Secondary

Measure	Time frame
% of patients where FFR CT would change upfront treatment strategy, cost effectiveness, % of non-evaluable CT	—

Countries

Europe

Contacts

Public ContactIngrid Lemoine

UZ Brussel Cardiology

ingrid.lemoine@uzbrussel.be003224779060

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026