Randomized study of FFR CT use for acute chest pain triage in the emergency department

Randomized study of FFR CT use for acute chest pain triage in the emergency department - Acute FFR CT trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024745

Enrollment

170

Registered

2019-07-01

Start date

2016-09-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute chest pain patients

Interventions

Exercise test and ECG plus coronary CT angio. If abnormal proceed to coronary angiography Coronary CT angio with virtual FFR. If abnormal proceed to coronary angiography

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Chest pain, GRACE score<140, Troponin T hs <0,052 or rise 0h-1h <0,005 mcg/l using Elecsys method, non-high risk ECG (ESC criteria)

Exclusion criteria

Exclusion criteria: no informed consent possible, limited life expectancy less than 2 years, other cardiac or non-cardiac diagnosis for chest pain, ACS, previous PCI or CABG, recent ACS within 6 months, arrhythmia, shock, acute heart failure, dynamic STT changes, contrast allergy, renal insufficiency, contra-indication to beta blockers or nitrates or adenosine, CHD

Design outcomes

Primary

Measure	Time frame
% of coronary angiograms showing obstructive CAD at 1 year and 3 years	—

Secondary

Measure	Time frame
MACE and individual components at 1 year and 3 years, cost-effectiveness, % of refused CT	—

Countries

Europe

Contacts

Public ContactIngrid Lemoine

UZ Brussel Cardiology

ingrid.lemoine@uzbrussel.be003224779060

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026