The study of algorithm for insulin dose after the change to insulin glargine U300 (LANTUS-XR) for type 2 diabetic patients with poor glucose control under insulin therapy.

The study of algorithm for insulin dose after the change to insulin glargine U300 (LANTUS-XR) for type 2 diabetic patients with poor glucose control under insulin therapy. - ISLAND STUDY

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024738

Enrollment

100

Registered

2016-11-07

Start date

2016-11-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

Self-titration group The attending physician changed Lantus to U300 without changing insulin dose at fisrt. Each patient in this group was instructed on SMBG and the algorithm of this study. The algo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Type 2 diabetes mellitus undertreatment for LUNTUS

Exclusion criteria

Exclusion criteria: Dementia Type 1 diabetes mellitus Patient with GAD antibody Hypoglycemia Hypersensitivity to LANTUS Pregnant Severe liver dysfunction Severe renal dysfunction

Design outcomes

Primary

Measure	Time frame
The percentage of cases where the absolute value improved by 1% or more or 10% or more from baseline HbA1c	—

Secondary

Measure	Time frame
fasting glucose level, weight change, Insulin dose	—

Countries

Japan

Contacts

Public ContactTetsuji Niiya

Matsuyama shimin Hospital Internal Medicine

t.niiya@matsuyama-shimin-hsp.or.jp81-89-943-1151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026