Novel approach to heart failure through the gut microbiota and its metabolite

Novel approach to heart failure through the gut microbiota and its metabolite - Prevention and treatment of heart failure through the gut

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000024701

Enrollment

Registered

2017-01-01

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: heart failure group =patients diagnosed as heart failure Control group =patients who have heart failure risk factors such as hypertension, diabetes, and/or arrhythmia, but who do not have heart failure.

Exclusion criteria

Exclusion criteria: 1) patients whose serum creatinine of greater than or equal to 3.0 mg/dL 2) patients with malignancy 3) patients with autoimmune disease or chronic inflammatory state 4) patients with inflammatory bowel diseases or intestinal surgery

Design outcomes

Primary

Measure	Time frame
To elucidate the characterization of gut microbial metabolites in the patients with heart failure.	—

Secondary

Measure	Time frame
Gut microbiota and its metabolites in feces after co-culture with prebioticas or probiotics in Kobe University Human Intestinal Model (KUHIM).	—

Countries

Japan

Contacts

Public ContactYamashita Tomoya

Kobe University Hospital Division of Cardiovascular Medicine

tomoya@med.kobe-u.ac.jp078-382-5111

Outcome results