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Efficacy of daiobotampito in the treatment of acute diverticulitis of colon: a single-center open-label randomized controlled trial

Efficacy of daiobotampito in the treatment of acute diverticulitis of colon: a single-center open-label randomized controlled trial - Trial about efficacy of daiobotampito in the treatment of acute diverticulitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024685
Enrollment
60
Registered
2016-12-01
Start date
2016-12-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diverticulitis of colon

Interventions

Patients are treated with fasting, antibacterial agents, and 7.5g per day of daiobotampito extract (Tsumura co.) for 10 days or not. Patients are treated with fasting, antibacterial agents. They are n

Sponsors

Gastrointestinal Medcine, Tokyo Saiseikai Central Hospital
Lead Sponsor
Center for Kampo Medicine, Keio University School of Medicine
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with diverticulitis who have strong pain (VAS > 50mm)

Exclusion criteria

Exclusion criteria: High probability to perforate. Diarrhea or soft stool. Chronic appetite loss, abdominal pain or diarrhea. Too friable. Insulin use. Immuno-compromised host. Pregnant or puerperal. Kidney disease (eGFR < 20 ml/min/1.73m^2). Allergy to daiobotampito. Experience to join in this trial before. Doctor's diagnosis as inappropriate.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale (VAS) of abdominal pain on day 3

Secondary

MeasureTime frame
VAS of abdominal pain other than day 3 Day on which VAS of pain becomes equal to or less than 50 mm Frequency of stool Frequency of ingravescence of diverticulitis, which patients need operation Frequency of adverse event

Countries

Japan

Contacts

Public ContactKoike, Hiroshi

Tokyo Saiseikai Central Hospital General Internal Medcine

koike-h@umin.ac.jp03-3451-8211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026