Cervical cancer Endometrial cancer
Conditions
Interventions
The concentration of indocyanine green (ICG) is 2.5 mg/mL. For each patient, a 25 mg vial with ICG powder is diluted in 10 mL of sterile water. We routinely inject 4 mL of the ICG solution into the ce
clock positions, 1 mL deep into the stroma and 1 mL submucosally on the right and the left of the cervix. Additionally, in patients with endometrial cancer, 2 mL of ICG is injected into the myometrium
Sponsors
Ciba University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients with endometrial cancer who are scheduled for retroperitoneal lymph node dissection or with stage 1A2 to 2A1 cervical cancer based on the International Federation of Gynecology and Obstetrics guidelines. 2. Over 20 years of age and under 70 years of age 3. Eastern Cooperative Oncology Group Performance status score 0-1 4. Patients who provides written informed consent
Exclusion criteria
Exclusion criteria: 1. Prior medical history of chemical sensitivity to indocyanine green 2. Detection of obvious lymph node swelling using CT or MRI 3. Extra-uterine dissemination 4. Patients on dialysis 5. Patients determine to be ineligible for any other reason by the physician in-charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of SLN | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity, false negative rate, and negative predictive value of SLN Accuracy of pathological diagnosis during surgery Adverse effects The number and location of the SLNs | — |
Countries
Japan
Contacts
Public ContactAkira Mitsuhashi
Graduate School of Medicine, Chiba University Reproductive Medicine
Outcome results
None listed