Pathophysiology and pathology diagnosis of adrenocortical disease causing aldosterone and cortisol excess

Pathophysiology and pathology diagnosis of adrenocortical disease causing aldosterone and cortisol excess - Pathophysiology and pathology aldosterone/cortisol excess diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000024604

Enrollment

500

Registered

2016-10-28

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary aldosteronism Cushing&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: primary aldosteronism: 200 cases Cushing's syndrome: 60 cases adrenocortical carcinoma: 10 cases adrenocortical incidentalomas: 50 cases others (pheochromocytoma, sex hormone producing tumor, etc.): 50 cases

Exclusion criteria

Exclusion criteria: not applicable

Design outcomes

Primary

Measure	Time frame
If surgical specimens have positive areas of P450-aldo and P450 11beta, we judge them as aldosterone and cortisol producing lesions, respectively.	—

Secondary

Measure	Time frame
Genetic abnormality will be detected in the aldosterone/cortisol producing lesions.	—

Countries

Japan

Contacts

Public ContactKoshiro Nishimoto

Saitama Medical University International Medical Center UroOncology

k.nishimoto@keio.jp042-984-4111

Outcome results