Difficult Asthma
Conditions
Interventions
None listed
Sponsors
Yamaguchi University Hospital Respiratory Medicine and Infectious Disease
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients will be eligible for inclusion in this study if all of the following criteria are met: 1.Patients with symptoms such as paroxysmal wheezing, cough, dyspnoea, etc., who are diagnosed with asthma based on a significant airway reversibility and / or airway hyperresponsiveness 2.Patients with step3 or 4 in asthma treatment by JGL 3.Patients are stable for at least 2 weeks prior to this study and can safely receive fiberoptic bronchoscopy. 4.Patients whose age is over 20 on informed consent acquisition date 5.Male and Female 6.Patients received an explanation of the study protocol and gave written informed consent. 7.Subjects are regardless of inpatients or outpatients.
Exclusion criteria
Exclusion criteria: Patients will be excluded in this study if any of the following criteria exist: 1.Patients have had an exacerbation for 2 weeks prior to this study and have been changed therapeutic strategy in stable status. 2.Patients judged as poor adherence to therapy.(ASK20 is used to assess it) 3.Patients are inadequate to include in this study.(EX: complication of malignant tumor).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of target molecules on BT | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of BT, Safety of BT, quality of life, physical activity | — |
Countries
Japan
Contacts
Public ContactTsunahiko Hirano
Yamaguchi University Hospital Respiratory Medicine and Infectious Disease
Outcome results
None listed