A preliminary genome-wide association study of plasma catechin concentration in Japanese individuals after ingestion of green tea catechins

A preliminary genome-wide association study of plasma catechin concentration in Japanese individuals after ingestion of green tea catechins - A preliminary GWAS of plasma catechin concentration in Japanese individuals after ingestion of green tea catechins

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024592

Enrollment

100

Registered

2016-10-27

Start date

2015-09-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Japanese adults

Interventions

Single oral dose of 1 g of green tea catechins in a fasting state

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects are competent to consent, keep the rules of the study. 2) We measure plasma catechin concentration in subjects 1 h after ingestion of catechins. The subjects are defined in terms of their plasma catechin concentration as follows: hyper-responders (plasma catechin concentration is more than upper flexion point) and hypo-responders (plasma catechin concentration is less than lower flexion point).

Exclusion criteria

Exclusion criteria: 1) Anemia 2) Subjects who are inadequate for enrollment judged by the investigator.

Design outcomes

Primary

Measure	Time frame
SNPs associated with plasma catechin concentration after 1 hour ingestion of catechins	—

Countries

Japan

Contacts

Public ContactMakoto Kobayashi, PhD

ITO EN, Ltd. Central Research Institute

m-kobayasi@itoen.co.jp0548-54-1247

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026