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Plasma orexin level in patients with delirium

Plasma orexin level in patients with delirium - Plasma orexin level in patients with delirium

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024565
Enrollment
70
Registered
2016-10-26
Start date
2017-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

delirium

Interventions

Obtain 10 mL of blood by venous puncture. Two time per patient. The first time is on 2nd-4th hospital day, and the second time is 10th-12th hospital day.

Sponsors

Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All inpatients in the geriatric ward in the Nagoya University Hospital.

Exclusion criteria

Exclusion criteria: 1. Patients taking suvorexant (antagonist of orexin receptors). 2. Patients planned to discharge before the 10th hospital day.

Design outcomes

Primary

MeasureTime frame
Difference in plasma orexin concentration between patients with and without delirium on the two to four hospital day.

Secondary

MeasureTime frame
1. Difference in plasma orexin concentration between on early hospital day (day 2 to 4) and on later hospital day (day 10 to 12) in patients with delirium on the early hospital day. 2. Difference in plasma orexin concentration between on early hospital day (day 2 to 4) and on later hospital day (day 10 to 12) in patients without delirium on the early hospital day.

Countries

Japan

Contacts

Public ContactHirotaka Nakashima

Nagoya University Hospital Centre for Community Liaison and Patient Consultation

naka621@med.nagoya-u.ac.jp052-744-1920

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026