Prospective, non-randomized, non-blinded clinical trial of granulocyte colony-stimulating factor for acute spinal cord injury

Prospective, non-randomized, non-blinded clinical trial of granulocyte colony-stimulating factor for acute spinal cord injury - Clinical trial of G-CSF for spinal cord injury

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024521

Enrollment

Registered

2016-10-21

Start date

2012-10-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal cord injury

Interventions

Granulocyte colony-stimulating factor 10 microgam/kg/day, intravenous infusion for 5 days conventional treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: acute spinal cord injury Neurological level of injury between C4 and C7

Exclusion criteria

Exclusion criteria: 1. allergy for G-CSF 2. Hematological malignancy 3. malignancy within 5 years 4. acute myocardial infarction 5. thorombosis 6. splenomegaly 7. consciousness disorder 8. pregnancy 9. neurological disorder which affects neurological evaluation

Design outcomes

Primary

Measure	Time frame
Change of ASIA motor score between baseline and three months after G-CSF administration	—

Countries

Japan

Contacts

Public ContactMasao Koda

Chiba University Graduate School of Medicine Department of Orthopedic Surgery

chibaseikei8f@yahoo.co.jp043-226-2961

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026