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Phase I clinical trial of WT1 vaccination for MDS with dose escalation

Phase I clinical trial of WT1 vaccination for MDS with dose escalation - Phase I clinical trial of WT1 vaccination for MDS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024497
Enrollment
3
Registered
2016-10-20
Start date
2016-10-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MDS

Interventions

Intradermal injection of WT1 peptides biweekly

Sponsors

Osaka University Dept of Cancer Immunology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients diagnosed as MDS HLA-A2402 Elevated WT1 expression in peripheral blood or bone marrow

Exclusion criteria

Exclusion criteria: Dysfunction of major organs

Design outcomes

Primary

MeasureTime frame
Frequencies of adverse events (Grade3,4)

Countries

Japan

Contacts

Public ContactNaoki Hosen

Osaka University Graduate School of Medicine Cancer Stem Cell Biology

hnaoki@imed3.med.osaka-u.ac.jp0668793676

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026