Hepatocellular carcinoma
Conditions
Interventions
Multiple administration of the optimal dosage
Sponsors
University of Tsukuba
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Between age of 20 to 75, who have agreement (2) Outpatients (3) Cirrhotic patients without uncontrollable ascites, who has no indication for resection, RFA, TACE or Sorafenib (4) Platelet counts less than 70,000/microL (5) Patient with the abnormal values in liver function tests (Alb, ALT, ChE, T-Bil, D-Bil) 6-month prior to registration (6) Less than four points of JIS score
Exclusion criteria
Exclusion criteria: (1) Acute hepatitis (2) Patients with HIV infection (3) Patients with a past history of cerebrovascular disease or cardiovascular disease (4) Bone marrow transplant recipients and immunosuppressed patients (5) Patient with plasma protein deficiency (eg. IgA deficiency) (6) Patients complicated with cerebrovascular disease, cardiovascular disease, pulmonary disease, renal disease, gastroenterological disease, hematological disease, and neurological or psychiatric disease (7) Patients with a cancer in other organs (8) Patients with HbA1c(NGSP) higher than 8.0 (9) Patients who is currently pregnant or consider pregnancy prior to the study (10) Patients who participated in another clinical trial within 6 months and received medications having pharmacologic effects on improving liver function or increasing platelet counts (11) Patients who have taken or who is currentry taking thrombopoietic agent (12) Patients with a past history of taking the Eltrombopag (13) Patients with allergic reaction to this medicine (14) Patients with allergic reaction to other medications (15) Patients with a past history of arterial or venous thromboembolism In addition, the patient who is judged to be inappropriate for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression free survival | — |
Countries
Japan
Contacts
Public ContactKurata Masanao
University of Tsukuba Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery
Outcome results
None listed