Individuals who shared a room with the index patient infected with influenza.
Conditions
Interventions
Individuals who shared a room with the influenza patient with a positive immuno-chromatographic test were given oseltamivir for three days as post-exposure prophylaxis.
Sponsors
Hokkaido University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patiets older than one year of age. 2. Individuals who shared a room with influenza patient (index case) with a positive immuno-chromatographic test were immediately separated from the index case by transferring to isolation room. 3. Oseltamivir for post-exposure prophylaxis was started within 48 hours after the onset of fever in the index case. 4. Written informed consent was obtained from each patient before enrolment.
Exclusion criteria
Exclusion criteria: 1. Patients with renal insufficiency (creatinine clearance less than 30 mL/min). 2. Patients older than 10 years and younger than 20 years. 3. Any other patients who are regarded as unsuitable for this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of this study is occurrence of influenza infection after a three-day regimen of oseltamivir as postexposure prophylaxis. Individuals who shared a room with the index patient infected with influenza were monitored for influenza-like symptoms for seven days after postexposure prophylaxis. | — |
Countries
Japan
Contacts
Public ContactNobuhisa Ishiguro
Hokkaido University Hospital Infection Control Team
Outcome results
None listed