Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as COPD by a physician. 2. modified MRC Grade; 1 to 3 3. disease condition stable by standard treatment 4. regular outpatient 5. acquisition of written informed consent
Exclusion criteria
Exclusion criteria: 1.Difficulties to walk due to musculoskeletal abnormality or neurological disease. 2.use of steroidal anti-inflammatory drugs in the past 6 weeks (oral prednisone more than 20mg/day) 3.currently on treatment of malignant disease, or cured but within 5-year disease free period 4.having completed pulmonary rehabilitation program within 6 months 5.implanted heart pacemaker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of the lower limb / knee extension muscle strength after 12 weeks of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the physical function (handgrip strength, gait speed, 6 min walk test), quality of life (CAT-COPD Assesment Test), ADL (ADL-D score)and COPD grade (modified BORG scale, BODE index) after 12 weeks of intervention | — |
Countries
Japan
Contacts
Kyoto University Graduate School of Medicine Department of Human Health Sciences