Research of the blood levels of hepatokines during meals and an oral glucose tolerance test

Research of the blood levels of hepatokines during meals and an oral glucose tolerance test - Research of the blood levels of hepatokines during meals and OGTT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000024411

Enrollment

Registered

2016-10-14

Start date

2014-09-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impaired glucose tolerance

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with type 2 diabetes or impaired glucose tolerance 2) Patients suspected impaired glucose tolerance who fits these conditons a. BMI >= 25 b. fasting blood glucose levels >= 100mg/dL c. blood glucose levels at any time >= 140mg/dL d. HbA1c >= 6.0% e. Patients have dyslipidemia or fatty liver

Exclusion criteria

Exclusion criteria: 1) Pregnant 2) Steroid pulse treatment 3) Current malignancy 4) Anemia under Hb 9g/dL 5) Liver chirrhosis (Child-Pugh score C) 6) Over diabetes over HbA1c 9%(NGSP) will not be included in oral glucose tests

Design outcomes

Primary

Measure	Time frame
Changes of blood levels of selenoprotein P and LECT2 during meal and an oral glucose test	—

Secondary

Measure	Time frame
Correlation of hepatokines and biomarkers (blood glucose, IRI, GLP-1, GIP, ACTH, cortisole, GH) or basic profiles of the subjects	—

Countries

Japan

Contacts

Public ContactTakamura Toshinari

Kanazawa University Hospital Endocrinology and Metabolism 1

ttakamura@m-kanazawa.jp076-265-2233

Outcome results