The effect of ramelteon to prevent emergence agitation after general anesthesia in pediatric patients : a randomized placebo- controlled trial

The effect of ramelteon to prevent emergence agitation after general anesthesia in pediatric patients : a randomized placebo- controlled trial - The effect of ramelteon to prevent emergence agitation after general anesthesia in pediatric patients : a randomized placebo- controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024379

Enrollment

Registered

2016-10-24

Start date

2016-10-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The pediatric patients undergoing tonsillectomy

Interventions

45-60min before anesthesia, pateients take ramelteon0.1mg/kg melted with syrup. 45-60min before anesthesia, pateients take lactose melted with syrup.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status 1 or 2 and scheduled to undergo tonsillectomy under general anesthesia are included in this study.

Exclusion criteria

Exclusion criteria: Patients are excluded from the study if they have the medial history such as mental retardation, mental disease, taking psycotropics or anticonvulsants, cardiac disease and cerebral surgery. Patients who enter hospital on the a.m. of the day of surgery are also excluded.

Design outcomes

Primary

Measure	Time frame
The emergence agitation in PACU(PAED scale>10)	—

Countries

Japan

Contacts

Public ContactMaya Komazaki

Kanagawa Children's Medical Centre Department of Anesthesiology

maya.koma05peony.root.dike@gmail.com045-711-2351

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026