1. Inpatients with major depressive disorder 2. Healthy controls.
Conditions
Interventions
None listed
Sponsors
Department of Neuropsychiatry, Keio University, School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [Patients with depression] 1) Inpatients at Department of Neuropsychiatry, Keio University Hospital. 2) Major depressive disorder according to DSM5. 3) Twenty years or older of age and being capable of providing consent or presence of substitute decision maker. 4) Being supposed to receive ECT and/or antidepressant treatment. [Healthy controls] 1) Volunteers who was matched age and gender to the patients with major depressive disorder who receive electroconvulsive therapy. 2) No presence of any psychiatry diagnosis. 3) No presence of psychiatry history. 4) Twenty years or older of age and being capable of providing consent.
Exclusion criteria
Exclusion criteria: [Patients with depression] 1) Presence of unstable physical illness. 2) History of electroconvulsive therapy for the past 6 months. 3) History of alcohol or any substance abuse for the past 6 months. 4) History of head trauma accompanied with severe neurological aftereffects. 5) History of vagal reflex induced by blood draw. [Healthy controls] 1) Presence of unstable physical illness. 2) History of vagal reflex induced by blood draw. 3) Those who are involved in this research. 4) Those who are exposed to potential pressure from investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in trace substances in peripheral blood following electroconvulsive therapy. | — |
Countries
Japan
Contacts
Public ContactHiroyuki Uchida
Keio University School of Medicine Department of Neuropsychiatry
Outcome results
None listed