Biochemical analysis of tear composition in dry eye patients

Biochemical analysis of tear composition in dry eye patients - Biochemical analysis of tear composition

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000024370

Enrollment

100

Registered

2016-10-17

Start date

2015-09-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Dry eye patients (defined by the diagnostic criteria of Japan dry eye society 2006)

Exclusion criteria

Exclusion criteria: 1) Complication of anterior disease(blepharitis, lagophthalmos, blepharospasm and iritis) other than dry eye ( patients with past history of the above disease are included). 2) Patients who were assessed as inadequate.

Design outcomes

Primary

Measure	Time frame
Tears are colloected by Schirmer test strips from the dry eye patints, which are clinically performed. After the elution of tear protein and lipid, total protein and lactoferrinm lipocalin, lysozyme and secretory IgA are measured. And cytokines, phospholipase A2, lipids are fractioned and quantified.	—

Countries

Japan

Contacts

Public ContactChika Shigeyasu

Kyorin University School of Medicine Department of Ophthalmology

shigeyasu@eye-center.org0422-47-5511

Outcome results