The effects of phenylephrine on oxygenation during one-lung ventilation; a randomized, double-blind, cross-over study

The effects of phenylephrine on oxygenation during one-lung ventilation; a randomized, double-blind, cross-over study - The effects of phenylephrine on oxygenation during one-lung ventilation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024317

Enrollment

Registered

2016-10-06

Start date

2016-10-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult patients undergoing elective thoracic surgery in the lateral decubitus position with at least 70 minutes of one-lung ventilation

Interventions

Intravenous phenylephrine infusion (20 mL/h = 15 mcg/min) for 30 minutes Normal Saline infusion at a speed of 20 mL/h for 30 minutes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients with ASA physical status 1-3 undergoing elective thoracic surgery in the lateral decubitus position with at least 70 minutes of one-lung ventilation

Exclusion criteria

Exclusion criteria: History of stroke, uncompensated cardiac disease, or arrhythmias

Design outcomes

Primary

Measure	Time frame
Arterial oxygen pressure after intervention	—

Secondary

Measure	Time frame
Mean Arterial Pressure, HeartRate, Pulse Pressure Variation, Perfusion Index, and Difference between Bladder Temperature and Skin Temperature	—

Countries

Japan

Contacts

Public ContactKohei Godai

Kagoshima University Hospital Department of Anesthesiology

kouhei84@m2.kufm.kagoshima-u.ac.jp+81-99-275-5430

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026