Study on the binding of constituents in eye-drops to aqueous humor albumin and the effect of drug efficacy

Study on the binding of constituents in eye-drops to aqueous humor albumin and the effect of drug efficacy - Study on the binding of drug to proteins in aqueous humor

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024310

Enrollment

200

Registered

2016-10-06

Start date

2015-09-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Interventions

Collection of aqueous humor and blood samples from subjects with treatment with glucose Collection of aqueous humor and blood samples from subjects without treatment with glucose

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The patient is twenty or over when the informed consent was gotten. 2. The patient who received satisfactory explanations and understood truly and the patient who was agreed to the informed consent by his own free will.

Exclusion criteria

Exclusion criteria: 1. The patient who has lack of capacity to give informed consent owing to some mental disorder. 2. The patient who needs a legal guardian. 3. The diabetic patient with HbA1c equal to or greater than 6.5 %. 4. The patient who is not applicable to cataract operation. 5. The case of cataract except for senile cataract. 6. The others the patient who the person responsible for study judged to be unsuitable.

Design outcomes

Primary

Measure	Time frame
The binding affinity of diclofenac sodium to albumin in aqueous humor of each patient.	—

Countries

Japan

Contacts

Public ContactSaya Ishii

University of Myazaki Hospital Department of Pharmacy

sayaishii38@gmail.com0985-85-9429

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026