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Association between telomere length and clinical indices in patients with idiopathic pulmonary fibrosis

Association between telomere length and clinical indices in patients with idiopathic pulmonary fibrosis - Telomere length in idiopathic pulmonary fibrosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000024289
Enrollment
120
Registered
2016-10-07
Start date
2016-11-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic pulmonary fibrosis (IPF)

Interventions

None listed

Sponsors

Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
Lead Sponsor
Center for Genomic Medicine, Kyoto University. Department of Respiratory Medicine, Tenri Hospital. Department of Respiratory Medicine, Kobe City Medical Center General Hospital. Department of Respiratory Medicine, Kobe City Medical Center West Hospital. Department of Respiratory Medicine, Takatsuki Red Cross Hospital. Respiratory Disease Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital. Department of Respiratory Medicine, National Hospital Organization Ibarakihigashi National
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients diagnosed with idiopathic pulmonary fibrosis based on guidelines of an official ATS/ERS/JRS/ALAT statement.

Exclusion criteria

Exclusion criteria: (A)Retrospective study; patients who experienced the onset of malignant disease within 3 years from first visit for our hospital. (B)Prospective study; (1) Patients with complication of malignant disease. But the patients who received complete resection or successful remission induction, and survived for more than 3 years without evidence of recurrence are eligible. (2) Patients who have been received more than 10mg/day of prednisolone or antifibrotic agents within 6 months. (3) Patients with acute exacerbation of IPF, respiratory infection, or pneumothorax within 4 weeks.

Design outcomes

Primary

MeasureTime frame
Reduction in the telomere length attrition rate by administration of antifibrotic agent.

Countries

Japan

Contacts

Public ContactTomohiro Handa

Graduate School of Medicine, Kyoto University Department of Respiratory Medicine

hanta@kuhp.kyoto-u.ac.jp075-751-3830

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026