Effect of milk protein hydrolysates intake on higher cerebral functions in elderly persons.

Effect of milk protein hydrolysates intake on higher cerebral functions in elderly persons. - Effect of milk protein hydrolysates intake on cerebral functions in elderly persons.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024281

Enrollment

Registered

2016-10-04

Start date

2016-10-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Milk protein hydrolysates (40mg/kg-bw, single dose) Milk protein (40mg/kg-bw, single dose) Dietary Fiber (40mg/kg-bw, single dose)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects who can receive a MRI examination. 2) Subjects who have no problems in daily life.

Exclusion criteria

Exclusion criteria: 1) Subjects with MMSE test score less than 24. 2) Subjects with cognitive impairment by cerebrovascular disease or Alzheimer's disease. 3) Subjects with heart disease. 4) Subjects who had heart attack or cerebral stroke within 6 months. 5) Subjects with acute hepatic dysfunction or active chronic viral hepatitis. 6) Diabetic patients with retinopathy or nephropathy or history of hypoglycemic attack or fasting blood glucose more than 200mg/dl. 7) Subjects with systolic blood pressure more than 180mmHg or diastolic blood pressure more than 110mmHg. 8) Subjects with acute orthopedic pain or neurologic manifestation. 9) Subjects with osteoporosis and history of compression fracture. 10) Subjects with milk allergy. 11) Subjects who regularly use supplements that may influence cerebral function; e.g. DHA, EPA, Catechin. 12) Patients who are judged inappropriate for the study by principal investigator.

Design outcomes

Primary

Measure	Time frame
Reaction time of cognitive test	—

Secondary

Measure	Time frame
Correct answer ratio of test Functional MRI	—

Countries

Japan

Contacts

Public ContactKen Kimura

Tokyo Denki University School of Engineering, Department of Humanities and Social Science

kimura@cck.denki.ac.jp03-5284-5635

Outcome results