Comparison of different dialysis modality (conventional hemodialysis and on-line hemodiafiltration) on coronary and lower limbs' arterial calcification. ~Multicenter interventional study.

Comparison of different dialysis modality (conventional hemodialysis and on-line hemodiafiltration) on coronary and lower limbs' arterial calcification. ~Multicenter interventional study. - Effect of hemodialysis and online hemodialysis on vascular calcification

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024241

Enrollment

100

Registered

2016-10-01

Start date

2016-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic renal failure

Interventions

switch from 6 months&#39

hemodialysys treatment to 6 months&#39

online hemodialysis treatment, and compare the progression of coronary artery and lower limbs&#39

calcification score.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with more than 12 weeks of hemodialysis vintage who gave written informed consent

Exclusion criteria

Exclusion criteria: 1)in hospital treatment within prior 12 weeks 2)have some infection or fever 3)atrial fibrillation 4)stent implanted in coornary artery or lower Limbs' artery 5)planned major amputation of lower limbs 6)severe cardiac failure with EF < 25% 7)warfarin user 8)involuntary movement of lower limbs 9)could not hold breath 10) pregnancy

Design outcomes

Primary

Measure	Time frame
Coronary artery calcification score and lower limbs' arterial calcification at study entry, 26 weeks, and 52 weeks, and compare them between hemodialysis and online hemodiafiltration.	—

Secondary

Measure	Time frame
change of serum phosphate, calcium, intact parathyroid hormone, C reactive protein, albumin, beta2 microglobulin, ankle brachial pressure index, toe brachial pressure index, skin perfusion pressure, cardiac ultrasonography in hemodialysis and online hemodiafiltration.	—

Countries

Japan

Contacts

Public ContactTakayasu Ohtake

Shonan Kamakura General Hospital Kidney and Dialysis Center

ohtake@shonankamakura.or.jp+81-467-46-1717

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Comparison of different dialysis modality (conventional hemodialysis and on-line hemodiafiltration) on coronary and lower limbs&#39; arterial calcification. ~Multicenter interventional study.