A study of early phase opioid induction in radiation therapy for head and neck cancer

A study of early phase opioid induction in radiation therapy for head and neck cancer - A study of early phase opioid induction in radiation therapy for head and neck cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024233

Enrollment

Registered

2016-09-30

Start date

2016-09-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

2 arm comparing trial. * Early phase opioid group: When amount of ingestion is gained, start administrating Acetaminophen 3200mg/day (4times before every meal and sleep) and Oxycodone 10mg/day (per 1

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Head and neck cancer patient 2) 3 methods (Radiation alone, Chemoradiation with CDDP, Chemoradiation with cetuximab) 3) No every pain killer use when therapy start 4) Possible to ingestion 5) Labo data shown below are requiered a) AST <100IU/L b) ALT <100IU/L c) Total bilirubin < 2.0 mg/dl 6) No psychorogical disease such effect on daily living and personal relation 7) Patients admission for participate this trial is obtained

Exclusion criteria

Exclusion criteria: Do not required the criteria shown above

Design outcomes

Primary

Measure	Time frame
rate of pain (NRS score),ingestion interruption	—

Secondary

Measure	Time frame
amount of total opioid, amount of ingestion, weight loss, rate of adverse event, clinical response rate, days of hospitalization	—

Countries

Japan

Contacts

Public ContactChihiro Kanno

International university health and welfare university Mita hospital Head and neck oncology center

chihiri@iuhw.ac.jp03-3451-8121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026