The study on pathophysiology of neurocognitive disorders by 18F-THK5351 PET

The study on pathophysiology of neurocognitive disorders by 18F-THK5351 PET - Tau PET for early dementia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024215

Enrollment

125

Registered

2016-09-29

Start date

2016-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment Alzheimer disease Dementia with Lewy bodies

Interventions

Tau PET, MRI, Neuropsychological test Tau PET, MRI, Neuropsychological test

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Disease group: Subjects who experienced brain MRI and neuropsychological test and suspected to be dementia or MCI. Provide informed consent and adhere to the protocol. Control group: Subjects without past or current history of cognitive dysfunction and with normal findings by neuropsychological test. Provide informed consent and adhere to the protocol.

Exclusion criteria

Exclusion criteria: With past history of brain disease or traumatic brain injury With severe lifestyle-related disease With cancer or cardiac disease

Design outcomes

Primary

Measure	Time frame
Degree of tau accumulation and distribution in the disease brain.	—

Countries

Japan

Contacts

Public ContactKazunari Ishii

Kindai University Faculty of Medicine Neurocognitive Disorders Ceneter

ishii@med.kindai.ac.jp072-366-0221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026