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Patient preference for monthly bisphosphonate versus weekly bisphosphonate in a cluster-randomized, open-label, crossover trial

Patient preference for monthly bisphosphonate versus weekly bisphosphonate in a cluster-randomized, open-label, crossover trial - Patient preference for monthly bisphosphonate versus weekly bisphosphonate

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024211
Enrollment
140
Registered
2016-09-29
Start date
2012-09-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with primary osteoporosis

Interventions

The clinics were randomized into two groups according to the dosing protocol, monthly bisphosphonate (3 months) followed by weekly bisphosphonate (3 months) or weekly bisphosphonate (3 months) followe

Sponsors

Clinical practice-based osteoporosis conference
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria were age more than 50 years, a fully ambulatory status, a diagnosis of primary osteoporosis according to the Japanese diagnostic criteria and an osteoporosis treatment-naive status.

Exclusion criteria

Exclusion criteria: The exclusion criteria were a history of reflux esophagitis, gastric or duodenal ulcer, gastrectomy, renal failure, or bone diseases including cancer-induced bone loss, primary hyperparathyroidism, hyperthyroidism, Cushing syndrome, multiple myeloma, Paget's disease of the bone, rheumatoid arthritis, or osteogenesis imperfecta.

Design outcomes

Primary

MeasureTime frame
Patient preference for either monthly bisphosphonate regimen or weekly bisphosphonate regimen among patients responding to the questionnaire after 6-month of treatment with monthly bisphosphonate (3-month) and weekly bisphosphonate (3-month)

Secondary

MeasureTime frame
Convenience of monthly bisphosphonate regimen compared tih weekly bisphosphonate regimen among patients responding to the questionnaire

Countries

Japan

Contacts

Public ContactJun Iwamoto

Keio University School of Medicine Institute for Integrated Sports Medicine

jiwamotoexmed@gmail.com03-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026