SuPerIoR antIdepressanT Effect of Duloxetine in Japanese patients with post-stroke depression

SuPerIoR antIdepressanT Effect of Duloxetine in Japanese patients with post-stroke depression - SPIRITED Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024197

Enrollment

Registered

2016-09-27

Start date

2016-10-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke depression

Interventions

Duloxetine other anti-depressant

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who agree to participate in this study and provide their informed consent; (2) aged between 20 and 85 years; (3) since after stroke over 1 month; (4) stroke type is only intracranial hemorrhage or ischemic stroke; (5) inpatients for the rehabilitation therapy; (6) stable general condition.

Exclusion criteria

Exclusion criteria: (1) previous unstable medical condition; (2) severe hepatic or renal dysfunction; (3) severe higher cortical dysfunction; (4) patients whose impairment severlities changed during the study period

Design outcomes

Primary

Measure	Time frame
Fugl-Meyer Assessment (FMA) and Functional independence Measure (FIM)	—

Secondary

Measure	Time frame
QIDS-J score, Japan Stroke Scale (JSS-DE), Apathy scale, Numerical Rating Scale (NRS), 10m-walk test, Rivermead Mobility Index (RMI)	—

Countries

Japan

Contacts

Public ContactShuji Matsumoto

Kagoshima University Dept. of Rehabilitation

shushu@m.kufm.kagoshima-u.ac.jp0995-78-2538

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026