Colorectal polyp
Conditions
Interventions
Colorectal polypectomy with switching warfarin to DOAC
Sponsors
Kurashiki Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects must satisfy all of the following criteria to be enrolled in the study 1.Age:over 20 years-old and under 90 years-old 2.concomitant use of warfarin 3.Colorectal polyps available to be resected by EMR or polypectomy 4.Cardiologist permitted switching warfarin to DOAC(patient with nonvalvular atrial fibrillation or deep vein thrombosis or pulmonary vein thrombosis, without severe renal failure: CCr >30ml/min, without any other contraindication to DOAC) 5.Written informed consent to continue DOAC after this study was obtained 6.Discontinuation or switching to aspirin/cilostazol is available in case of taking thienopyridine derivative 7.Written informed consent for this study was obtained
Exclusion criteria
Exclusion criteria: Potential subjects who meet any of the following criteria will be excluded from participating in the study 1.pregnant or breast-feeding 2.patient with inflammatory bowel disease or familial polyposis 3.without bleeding tendency(Platelet count <90,000/uL at the screening visit) 4.poor bowel preparation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delayed bleeding and thromboembolic event | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of immediate bleeding and perforation, hospitalization | — |
Countries
Japan
Contacts
Public ContactYuichi Shimodate
Kurashiki Central Hospital Gastroenterology and Hepatology
Outcome results
None listed