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The influence of posture change on ocular flood flow and intraocular pressure in normal subjects.

The influence of posture change on ocular flood flow and intraocular pressure in normal subjects. - The influence of posture change on ocular blood flow and intraocular pressure in normal subjects.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024149
Enrollment
50
Registered
2016-10-31
Start date
2016-09-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteer

Interventions

Assessment of mean blur rate measured by laser speckle flowgraphy in both a sitting and a supine position.

Sponsors

Department of Ophthalmology, Toho University Ohashi Medical Center.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subjects who met all of the following inclusion criteria are included:normal findings on slit-lamp biomicroscopy and funduscopic examination,intraocular pressure less tthan 21mmHg,best-corrected visual acuity of at least 15/25,spherical refractie errors between -6.00 and +6.00 diopters,and arefractive cylindrical error within +/-2.00D and axial lengths less than 26mm.

Exclusion criteria

Exclusion criteria: Subjects who aren't satisfied with inclusion criteria.Subjects who have a history of intraocular surgery except for cataract. Subjects who have a clinically significant retina-choroidal disease,vitreous disease,or corneal disease.Subjects who have high systolic blood pressure over 150mmHg or high diastolic pressure over 90mmHg at rest.Subjects who are taking Ca blocker,or alpha-1 blocker,or beta-1 blocker,or Sildenafil.

Design outcomes

Primary

MeasureTime frame
Assessment of mean blur rate measured by laser speckle flowgraphy before and after posture change.

Secondary

MeasureTime frame
Correlation between mean blur rate, measurements of OCT and IOP.

Countries

Japan

Contacts

Public ContactHakuei Honda

Department of Ophthalmology, Toho University Ohashi Medical Center. Department of Ophthalmology

89ahonda@gmail.com03-3468-1251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026