Sequential Treatment Initiation with Japanese Cedar droplet and HDM tablet Sublingual Immunotherapy Followed by Simultaneous Treatment

Sequential Treatment Initiation with Japanese Cedar droplet and HDM tablet Sublingual Immunotherapy Followed by Simultaneous Treatment - STJc&M Study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000024129

Enrollment

Registered

2016-09-25

Start date

2016-09-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis

Interventions

Patients are received Japanese Cedar droplet from October 2016. Patients are received HDM tablet from November 2016. The dosing inerval is 5 minutes.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)A history of Japanese cedar pollinosis and House dust mite allergic rhinitis before study entry. (2)Anti-Japanese ceder pollen IgE antibodyand Anti-House dust mite IgE antibody are positive (3)Positive house dust mite allergen provocation test (4)Written informed consent is required

Exclusion criteria

Exclusion criteria: (1)Received Japanese cedar pollen or house dust mite aleergen immunotherapy (2)Taking any immunosuppressive drugs or any anticancer drugs (3)Patients with upper respiratory inflammation, respiratory infection, or severe bronchial asthma (4)Patients with severe cardiac, hepatic, kidney disease (5)Pregnant women and those at risk of pregnancy, lactating woman (6)Recruited anothere clinical trial within 6 month (7)Patients who the doctor judged inaproppriate for the study

Design outcomes

Primary

Measure	Time frame
Evaluation of adverse events in CTCAE v4.0 and Grading system for SLIT local AEs	—

Secondary

Measure	Time frame
Symptom score,VAS, QOL Questionaire score(RQLQ,JRQLQ), Change of Biomarkers in blood	—

Countries

Japan

Contacts

Public ContactTomokazu Matsuoka

University of Yamanashi Department of Otorhinolaryngology, Head & Neck Surgery

tmatsu@yamanashi.ac.jp055-273-6769

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026