Skip to content

Clinical efficacy and safety of percutaneous transhepatic portal embolization (PTPE) with N-butyl 2-cyanoacrylate-lipiodol-ethanol (NLE) before liver resection

Clinical efficacy and safety of percutaneous transhepatic portal embolization (PTPE) with N-butyl 2-cyanoacrylate-lipiodol-ethanol (NLE) before liver resection - Clinical efficacy and safety of PTPE with NLE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024103
Enrollment
10
Registered
2016-10-01
Start date
2016-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma,intrahepatic cholangiocarcinoma,metastatic liver tumor

Interventions

Perform PTPE with NLE before 3-4 weeks for right hepatic lobe resection. NLE injection volume is determine to measure the portal vein branch of the volume of the right hepatic lobe in advance.

Sponsors

Wakayama medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) case of right hepatic resection of residual liver volume less than 40% 2) 20 years of age or older and less than 80 years of age, gender is unquestioned 3) Performance status; 0,1,2 4) child-pugh grade ; A 5) Bone marrow and renal function is maintained in the preoperative clinical examination within two weeks WBC: more than 3,000/mm3, less than 12,000/mm3 Plt: more than 70,000/mm3 Hb: more than 10.0g/dL Cr: less than 1.5mg/dL

Exclusion criteria

Exclusion criteria: 1) Ascites 2) Patients with a bleeding tendency(Plt: less than 50,000/mm3, PT-INR: more than 1.5) 3) poor renal function(eGFR: less than 30 ml/min/1.73m2)

Design outcomes

Primary

MeasureTime frame
Procedure-related complications

Secondary

MeasureTime frame
Adverse event,increase rate of residual liver volume ,changes in liver function before and after the PTPE, the portal vein recanalization

Countries

Japan

Contacts

Public ContactAkira Ikoma

Wakayama medical university Department of Radiology

yfb04322@nifty.com073-441-0605

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026