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The effectiveness of cognitive behavioral therapy and the alternation of brain magnetic resonance imaging.

The effectiveness of cognitive behavioral therapy and the alternation of brain magnetic resonance imaging. - The effectiveness of CBT and the alternation of brain MRI.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024087
Enrollment
1100
Registered
2016-09-20
Start date
2015-09-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression Anxiety disorder Obsessive compulsive disorder Autism spectrum disorder Attention deficit/hyper activity disorder Adjustment Disorder Feeding or eating disorders Somatic Symptom Disorder

Interventions

Cognitive behavioral therapy From 12 to 35 times No treatment

Sponsors

Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Research Center for Child Mental Development, Chiba University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Patient with depression, anxiety disorder, obsessive compulsive disorder, autism spectrum disorder and attention deficit/hyper activity disorder, and adjustment disorder diagnosed by DSM-IV-TR , DSM-5, DSM-5-TR. 2)Healthy control 3)People with subthreshold anxiety: those who have more than moderate or greater symptoms measured by LSAS, or any new student who answers "yes" to anxiety symptoms on the mental health checkup questionnaire and shows moderate or higher anxiety as measured by STAI questionnaire in the post-checkup interview.

Exclusion criteria

Exclusion criteria: 1)organic brain disorder 2)active suicidality 3)antisocial personality disorder 4)other severe mental / physical condition

Design outcomes

Primary

MeasureTime frame
PHQ-9:Patient Health Questionnaire GAD-7:Generalized Anxiety Disorder

Secondary

MeasureTime frame
Beck Depression Inventory 2nd :BDI-II Liebowitz Social Anxiety Scale :LSAS Obsessive Compulsive Inventory :OCI Autism-Spectrum Quotient :AQ-50 EuroQol 5 Dimension :EQ-5D Brain MRI Resting-state functional MRI, T1-weighted image, Diffusion tensor imaging Cognitive function test The following items are used according to the age and the disorder of a subject. STAI SCAS OCD-CV MOCI Y-BOCS CY-BOCS DY-BOCS SCSQ AQ Children's version PARS ADOS ADI-R Vineland-II RAADS-14 ADHD-RS FAD SSS CBCL BAI SDS DSRS SCQ SRS YSQ SMI Fear of Compassion Scale DOCS OBQ-44 SI-R PedsQL C-OCI RBS-R QCD General Questionnaire Sheet Ministry of Health, Labour and Welfare in Japan, Standard health screening and health guidance program IES-R Structured Clinical Interview For DSM-5 Disorders Research Version IPAQ, short version, usual week ERQ-CA EAC-C EAC-A Japanese Version of the Highly Sensitive Person Scale DASS-21 AIS ISI EDEQ EDE 17.0D ver. MCQ-30 BCQ BSQ MSPQ GCS CGI-S BPI-J PHQ-A ECR-RC9 CSQ-8J TKSS, Japanese version

Countries

Japan

Contacts

Public ContactYoshiyuki Hirano

Research Center for Child Mental Development Chiba University Department of Cognitive Information Technology

hirano@chiba-u.jp043-226-2975

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026