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Evaluation to the effects on the tear film lipid layer of 3% Diquafosol Sodium ophthalmic solution for Dry Eye patients with Meibomian gland dysfunction.

Evaluation to the effects on the tear film lipid layer of 3% Diquafosol Sodium ophthalmic solution for Dry Eye patients with Meibomian gland dysfunction. - Effects of 3% Diquafosol Sodium ophthalmic solution for Dry Eye patients with MGD.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024041
Enrollment
100
Registered
2016-09-20
Start date
2016-09-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye patients with Meibomian gland dysfunction

Interventions

3% Diquafosol sodium ophthalmic solution Soft Santear

Sponsors

Itoh Clinic Department of Ophthalmology
Lead Sponsor
Itoh Clinic
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Over 20years old Male and Female Patients diagnosed as dry eye by 2006 diagnostic criteria for dry eye with Superficial punctate keratopathy. Patients with MGD Tear film lipid layer thickness is less than 75nm by LipiView

Exclusion criteria

Exclusion criteria: High degree of eye damage due to Stevens-Johnson syndrome, or ocular pemphigoid, etc. Infection of keratoconjunctival or eyelid. Obvious ocular surface or eyelid disease (eyelid congenital anomaly, entropion, ectropion) There is an allergic disease in inspection time Daily wear of contact lenses (average four days a week or more of wearing is considered every day. Wear history, from time to time the wearer is inspection day remove) Patients with surgical history in the internal eye within 3 months prior to initiation of the clinical research. History of systemic disease or eye disease can affect the tear production and function Punctal plug insertion Lipid hypersecretion from the meibomian glands Patient even if the pressure on the eyelid in Arita Meibomian Gland

Design outcomes

Primary

MeasureTime frame
Tear film lipid layer thickness Tear film meniscus Symptoms Superficial punctate keratopathy Tear film breakup time Meibography meiboscore Tear volume

Countries

Japan

Contacts

Public ContactReiko Arita

Itoh Clinic Ophthalmology

ritoh@za2.so-net.ne.jp048-686-5588

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026